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These may include temporary skin irritation, slight redness, or increased sensitivity

requiring 2 alternate drugs under medical benefit but only 1 under pharmacy) or different prescribing restrictions ( [16] )

It is evaluated that half of all drug candidates are substrates for the P-gp efflux pump, presenting a reduced potential for systemic penetration to the CNS [7]

With knowledge of what not to do, the next section will look at recommendations from physicians for creating a smooth and efficient medical clearance process